Genes, Interdependent Organisms In Genomes Communes

Organisms Are Not Blue Prints

Dec 31, 2007

To: salk.edu

Re: Happy New Year

From

http://forum.physorg.com/index.php?showtopic=14988&st=135&#entry296678

Are Living Organisms “Genetic Blue Prints”?

A. An Elegant Work With Plant Cells

http://www.eurekalert.org/pub_releases/2007-12/si-nps122107.php

– The work comprised inactivating the exosome, for homing in on its RNA targets. The exosome is a molecular machine in charge of controlled RNA degradation, and “When you knock down exosome activity, you see changes in the transcriptome that are not visible under any other circumstance”, which -BTW – is like saying “when in a production line of a host of products you switch off the end-of-line QA (quality assurance) stand you see products not visible when the QA is on”…

– “Since the common notion is that the exosome plays a central role in bulk RNA turnover”, the researchers say, they expected to find the levels of all transcripts increasing when they inactivated the exosome complex. “But not everything is going up, instead the exosome mechanism seems to be very tightly regulated,” says Ecker. “We didn’t see regions that are known to be silenced to go up, instead we found a very specific group of transcripts that are regulated in this way. Among them are regular protein-coding RNAs, RNA processing intermediates and hundreds of non-coding RNAs, the vast majority of which hadn’t been described before.” ( I.e. products normally removed by the QA unit… DH ).

– “These strange transcripts are associated with small RNA-producing loci as well as with repetitive sequence elements,” says Gregory. “They are under very tight regulation by the exosome, but we still don’t know exactly what this means.”

B. Still, Don’t Know What This Mean…

I suggest again and again ad absurdum what should be clear to every human with plain common sense, that “This Means” that living organism, the interdependent genes, and their communal genome association, are not “Genetic Blueprints Into Molecular Building Blocks”. You and I do not become any more “genetic blueprints” when we carry out any process or operation than our genes-genomes thus become “genetic blueprints” when they carry out their processes or operations…

With best new year greetings to all our genetic blueprints forum members,

Dov Henis

——————

PS:

Again, The biggest hindrance of scientific, and even technological, progress in comprehension and exploitation of Biology is the avoidance to accept-regard genes-genomes as organisms. And equally hindering is the lack of a term for genes-genome that explicitly and clearly defines them as organisms, as The Prime Cardinal Earth Life Organisms, distinguished from all cellular secondary stratum organisms.

This avoidance, which is fraught with implications about the nature of life, is also the biggest hindrance of human existential and social progress.

DH

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Wonders Of Mutual Recognition Of “Pieces Of DNA”

Jan 25, 2008

To Imperial College London

The Wonders Of Mutual Recognition Of “Pieces Of DNA”

Genes “Recognize Similarities In Each Other”

FYI: CC of

http://forum.physorg.com/index.php?showtopic=14988&st=150&#entry305432

A.

In “Genes Recognize Similarities In Each Other”, you report work done with “pieces of identical double-stranded DNA” that “Recognize Similarities In Each Other”, and findings that “according to the theory, this recognition mechanism is stronger the longer the (pieces of. DH) genes are”.

B.

You use the word ‘recognize’, derived from organism’s cognizance, not a term derived from inanimate affinity. Do you or don’t you wish to imply that a gene is an organism? why do you evade this point? Is the evasion accidental or intentional?

You may find the following definitely relevant and of interest:

1) “Life, Tomorrow’s Comprehension”

http://blog.360.yahoo.com/blog-P81pQcU1dLBbHgtjQjxG_Q–?cq=1&p=372

and

2) “Science Must Be Rescued From Its Guilds…”

http://forum.physorg.com/index.php?s=9aa2578c3e99328f1b7819ef6514a802&showtop…

C.

You continue with blurred terminology when you state:

“Understanding the precise mechanism of the primary recognition stage of genetic recombination may shed light on how to avoid or minimise recombination ERRORS in evolution, natural selection, and DNA repair. This is important because such errors are believed to cause a number of genetically determined diseases including cancers and some forms of Alzheimer’s, as well as contributing to aging. Understanding this mechanism is also essential for refining precise artificial recombination techniques for biotechnologies and gene therapies of the future”.

D.

Imperial College London,

please clarify…

Respectfully,

Dov Henis

PS: I’m prepared to clarify my comprehension of the likeness of genes, and its different cognizance from that of 2nd level organisms… if you are interested… DH

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The Evolutionary ‘Role’ Of Gene Variants

Feb 01, 2008

To DeCODE

The Evolutionary ‘Role’ Of Gene Variants

http://forum.physorg.com/index.php?showtopic=14988&st=150&#entry307281

The Evolutionary ‘Role’ Of Gene Variants,

Of Genes And Human Conceit, And

Of Inadequate Comprehension Of Life

1,2,3 are ” ” quotes from

http://www.physorg.com/news121010270.html

Single nucleotide polymorphism, SNP = a variant DNA sequence in which the purine or pyrimidine base (as cytosine) of a single nucleotide has been replaced by another such base (as thymine)

1) “Yet remarkably, the versions of the SNPs that increase recombination in men decrease it in women, and vice versa.”

Of course. Expected. Man and woman are different phenotypes of the human genotype. Each phenotype drives for its own ( Darwin…) survival…

2) “…enable the variants to help to maintain a fundamental tension crucial for evolutionary success: promoting the generation of significant diversity within a portion of the population…”

The ‘variants’ do not have cognizance and they do not give a damn about evolutionary success or promotion of diversity. They are organisms, with an innate Darwinian drive to survive. Plain and simple. Common sense…(no academic courses, no degrees, no professional guild…)

3) “…evolution appears to place a premium on the generation of human diversity…”.

Unfounded ‘pseudosophisticated verbiage. Evolution of life is but a minute component of the evolution of the universe. Cosmic evolution is the evolution of energy, and within it, life’s evolution is the evolution of genes-genomes, in a losing attempt to survive, to maintain – as long as possible – pockets of constrained energy that would otherwise expand and dilute with the whole mass and energy of the cosmos…

Dov Henis

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